Main navigation
The faculty of the UI Department of Biochemistry and Molecular Biology conduct research to gain new insights into the cellular and molecular mechanisms underlying normal and abnormal cellular processes, and their relevance as targets for improving health and treating disease.
Key areas of interest in the department include the study of pathways and mechanisms involved in the maintenance of genome integrity and protein homeostasis, in response to various stresses. We have a major focus on understanding the dysregulation of these processes in cancer and in aging. The biological settings in which we characterize these processes include normal physiology, bacterial and parasitic infection, cancer, neurodegenerative and other chronic diseases. Our experimental approach to these important topics is exceptionally broad, ranging from genetic engineering to live cell imaging to the study of molecules by X-ray crystallography, and likewise makes use of a range of genetically-tractable model organisms including mice, yeast, and worms.